TS-004709 — To improve the accuracy of mental health diagnosis, this online toolkit will provide an evidence-based assessment for patients, clinicians and providers.

TS-004707 — This IP is a gene therapy designed to treat cystic fybrosis using variants to improve stability and channel conductivity.

TS-004610 — This is a new approach to gene therapies in cells that are longer than 4.5 kb. By inhibiting DNA-PKcs and 53BP1, it allows the enrichment cassette in the second AAV to be replaced with genetic cargo, which consequently allows insertion for genes up to 6.5-7 kb.

TS-004608 —

TS-004602 — This mnemonic device condenses and standardizes clinical research processes by organizing responsibilities into five critical steps. Each task follows a consistent format found in the compact and portable reference guide.

TS-004522 — The hospital grade highcair has an adjustable seat, headrest, tray and footrest with an emphasis on security and durability.

TS-003412 — 4,800 pediatric patients undergo tracheostomies annually in the U.S., with multiple caregivers throughout their lives requiring training in the appropriate care. Nationwide Children’s Hospital simulation professionals have developed an innovative Pediatric Tracheostomy Task Trainer model. The manikin offers advanced features for more hands-on training, replicating real-life experiences, including applications such as CPR training. Existing commercially available task trainers have limitations, and the new model addresses these issues. The portable trainer caters to a broad audience, including healthcare professionals and students with tracheostomy tubes. Key skills associated with the device cover suctioning (both open and closed techniques), stoma care, tracheostomy tie changes, and rescue breathing through tracheostomy/face, depending on insertion availability. Notable improvements include advanced airway management and haptic feedback. The developed prototype has undergone successful training sessions for hospital staff and caregivers at Nationwide Children’s Hospital. Additionally, a provisional patent application has been filed. We are actively seeking commercial partners to license this technology in the training manikin market, projected to reach $2.60 billion by 2028 with an 11.2% compound annual growth rate.

TS-002700 — The use of tracheostomies is fairly common resulting in the need for cost-friendly and accessible training materials for tracheostomies. Nationwide Children’s Hospital researchers created the Tracheostomy Sim in a box, an innovative task trainer and educational tool designed for healthcare professionals, families and clinic staff working with patients with a tracheostomy. The trainer includes validated checklists to ensure that users effectively understand the educational contents.