Temperature responsive pigments can be mixed with a base material and undergo a visual color change when a threshold temperature is reached. The temperature sensitive pigments are commercially available for use in cosmetics; however, have not previously been utilized in medical simulations. Here, use of these pigments in silicone models will allow for an observable change in color to simulate tissue reactions to heat (i.e. use of a laser in medical procedures). Following the application of heat, and as the material cools below the threshold temperature, the model will return to its baseline appearance, thus allowing for multiple uses. So far, this has been tested in a simulation model for twin-to-twin transfusion syndrome; however, could be applied to any laser-based medical procedures.