TS-000635 — Infectious peritonitis is a serious complication in patients undergoing chronic peritoneal dialysis (PD) leading to patient morbidity and mortality. Currently available, non-specific diagnostic criteria of peritonitis can lead to missed /over-diagnosis. Researchers at Nationwide Children’s Hospital have discovered more sensitive and specific biomarker for peritonitis in the PD population that entails measurement of antimicrobial peptide levels. This new process will aid practitioners in early, accurate diagnosis of acute peritonitis in patients undergoing PD.

TS-000465 — Urinary Tract Obstruction (UTO) is one of the most common etiologies of prenatal hydronephrosis, a condition that can lead to permanent kidney damage if left untreated. A group of researchers at Nationwide Children’s Hospital have developed a new way to use specific uroepithelial proteins such as Antimicrobial Peptides (AMPs) as biomarkers of obstructive uropathy. This non-invasive procedure tremendously improves early detection of UTO, informs surgical management and enables postoperative monitoring of patients.