TS-005787 — This custom DNA methylation microarray is designed to assess long‑term health risks and recovery potential associated with early‑life nutritional stress and starvation, based on the discovery of unique DNA methylation signatures that distinguish individuals who survived severe childhood starvation and achieved advanced age (70–80 years).

TS-005784 — This novel, personalized hormone‑replacement therapy for anorexia nervosa (AN) simultaneously targets dysregulated ghrelin and leptin signaling using a transdermal skin‑patch delivery system. This represents a new device and treatment paradigm for AN, introducing both a previously undescribed hormone combination therapy and a precision‑medicine framework that tailors treatment based on epigenetic biomarkers, with strong translational potential supported by an existing, genomically characterized patient cohort.

TS-005666 — This new IP is an algorithm and data-storage framework designed to improve how large‑scale genetic datasets are stored, queried, and analyzed. By reorganizing genetic information into fixed groups, this eliminates the need to retain sensitive individual‑level data, reduces storage requirements, and enables rapid, on‑demand estimation of allele frequencies across datasets.

TS-005489 — This technique for genetic testing uses polygenic risk scores as a measure of susceptibility to skin cancers for individuals with hypothyroidism. Diagnosis of hypothyroidism has been correlated with increased risk of skin cancer, while genetic susceptibility to hypothyroidism has been correlated with decreased risk of skin cancer. Using polygenic testing, subjects with top 10% polygenic risk scores have neutral to decreased risk, while subjects with bottom 10% scores have elevated risks of skin cancer.

TS-004605 — The polygenic scores (PGS) browser, a web-based application, improves precision medicine and calculates an individual’s genetic risk, providing access to over 3,000 PGS models and 10,000 studies.

TS-004604 — The polygenic scores (PGS) browser is a web-based application designed to improve precision medicine and calculate an individual’s genetic risk. The application provides users with access to a comprehensive and well-annotated database with over 3,000 PGS models. Users may select the most suita…