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Salvianolic Acid (SAA) Treatment of FSHD
TS-002175 — The third most common type of muscular dystrophy, Facioscapulohumeral Muscular Dystrophy (FSHD), affects over 870,000 individuals worldwide by causing debilitating pain, muscle weakness, fatigue along with many other symptoms in their face, shoulders, upper arms and lower legs. Researchers at Nationwide Children’s Hospital created a treatment using Salvianolic Acid (SAA) as a drug therapy for neuromuscular disorders including FSHD.
SAA, a natural compound found in the Salvia plant, has never been used for treating FSHD or any other neuromuscular disorder before. The compound inhibits protein methyltransferase (PRMT1), protects cells from double-homeobox gene 4 (DUX4) induced death and reduces the addition of methyl groups on t…
  • College:
  • Inventors: Harper, Scott; Eidahl, Jocelyn; Knox, Renatta; Wallace, Lindsay
  • Licensing Officer: Eidahl, Jocelyn

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