# of Displayed Technologies: 3 / 3


Gain of Function CFTR Variants to Enhance the Efficacy of Genetic Therapies Treat Cystic Fibrosis
TS-004707 — This IP is a gene therapy designed to treat cystic fybrosis using variants to improve stability and channel conductivity.
  • College:
  • Inventors: Vaidyanathan, Sriram
  • Licensing Officer: Mills, Joseph

Synergistic NHEJ Inhibition to Obtain Enrichment Free Sequential Insertion of Genes > 4 kb
TS-004610 — This is a new approach to gene therapies in cells that are longer than 4.5 kb. By inhibiting DNA-PKcs and 53BP1, it allows the enrichment cassette in the second AAV to be replaced with genetic cargo, which consequently allows insertion for genes up to 6.5-7 kb.
  • College:
  • Inventors: Vaidyanathan, Sriram
  • Licensing Officer: Mills, Joseph

Synergistic NHEJ Inhibition to Obtain Enrichment Free Sequential Insertion of Genes > 4 kb
TS-004608
  • College:
  • Inventors: Vaidyanathan, Sriram
  • Licensing Officer: Mills, Joseph

Loading icon