TS-000205 — Otitis media (OM) is a leading cause of hearing loss in children in the U.S. Nontypeable Haemophilus influenzae (NTHI) is a major causative agent of OM and other diseases of the respiratory tract. NTHI-mediated OM often persists despite repeated antibiotic therapies, due in part to the ability of NTHI to invade host epithelial cells. Researchers at Nationwide Children’s Hospital have developed a novel approach to treating or preventing OM by inhibiting Arp2/3-mediated invasion of host cells.

TS-000165 — Determining the severity of urinary tract infections (UTIs) relies on patient reporting of symptoms, a difficult task when working with pediatric populations. Failure to identify severe cases of UTI can result in dangerous complications including renal scarring and urosepsis. Researchers at Nationwi…