Available Technologies

Increasing Tissue Specific Gene Delivery by AAVrh74 Capsid Modification

Researchers at Nationwide Children's Hospital have identified modified capsid sequences of the Adeno-associated Virus rh74 (AAVrh74) native capsid that improve delivery of genes to specific target cells or overall global gene delivery. These include modifications that increase specific gene delivery to either the heart or muscle stem cells.

Patents

Patent # Title Country
ZL 201980018151.80 Increasing Tissue Specific Gene Delivery by Capsid Modification China
277270 Increasing Tissue Specific Gene Delivery by Capsid Modification Israel
7304878 Increasing Tissue Specific Gene Delivery by Capsid Modification Japan
2801217 Increasing Tissue Specific Gene Delivery by Capsid Modification Russia
11202008687X16/980,821 Increasing Tissue Specific Gene Delivery by Capsid ModificationIncreasing Tissue Specific Gene Delivery by Capsid Modification SingaporeUnited States of America
3,092,353 Increasing Tissue Specific Gene Delivery by Capsid Modification Canada
1120200183547 Increasing Tissue Specific Gene Delivery by Capsid Modification Brazil
10-2025-7023337 Increasing Tissue Specific Gene Delivery by Capsid Modification Korea, South
317905 Increasing Tissue Specific Gene Delivery by Capsid Modification Israel
2025204275 Increasing Tissue Specific Gene Delivery by Capsid Modification Australia
10-2025-7023347 Increasing Tissue Specific Gene Delivery by Capsid Modification Korea, South
19/277,998 Increasing Tissue Specific Gene Delivery by Capsid Modification United States of America

Tech ID

2018-002

College

(None)

Licensing Manager

Corris, Andrew
Andrew.Corris@nationwidechildrens.org
614-355-1604

Inventors

Categories

External Links

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