Cmah-Deficient mdx Mice: A Better Mouse Model for Duchenne Muscular Dystrophy

Putative cytidine monophosphate-N-acetylneuraminic acid hydroxylase-like protein is an enzyme that in humans is encoded by the CMAH gene. A new CMAH-Deficient mouse model for DMD-related research has been created. The CMAH-Deficient mouse model mimics the human disease better than the current standard model thus providing a model for DMD that facilitate translational research to be more relevant to issues affecting the human disease.

Available through Jax Labs:

Jax.org

Stock #017929

Stage of Development:
Development is Complete

Potential Applications/Markets:

It can be used to study development of drugs and biologics to treat Duchenne Muscular Dystrophy, therefore its primary application is in translational research.

Opportunity / Seeking:

Licensing

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